Within the INTERREG IIIB project MARS "Monitoring the Alpine Region's Sustainability", an international team under the lead of BAK Basel Economics is developing an integrated set of indicators for measuring and evaluating sustainable development in the alpine space. The set of indicators integrates economic, social and ecological aspects of sustainable development and provides the basis for benchmarking of the regions. MARS is based on an extended geographical alpine space and includes important regional centres like Vienna, Milano, Munich, Lyon and Bern. In Germany, the alpine space comprises the administrative districts of Oberbayern, Schwaben, Freiburg im Breisgau and Tübingen (NUTS 2 regions). For these regions and for the total German alpine region, a dataset for the generation of environmental indicators will be established. This comprises: domestic extraction and harvest of raw materials, Domestic Processed Output (DPO = emissions, wastes and dissipative use of products), water consumption, energy consumption, land use, and a feasibility study for the Direct Material Input (DMI = domestic extraction and harvest of raw materials plus imports). In addition, regional project partners from public administration and policy will be involved in order to consider their needs for data and indicators for sustainable development of their regions. The results of MARS shall thus support local actors in evaluating and planning regional policies.